On which chromosome is the HER2 and ERBB2 gene located?

The HER2 and ERBB2 gene is located on chromosome 17. This gene is known for its role in encoding a protein that is part of the human epidermal growth factor receptor family, which is significant in the regulation of cell growth and differentiation. The overexpression of HER2 is often associated with certain aggressive types of breast cancer, making it an important target for therapeutic interventions.

Chromosome 17 is integral to many studies related to cancer genetics, which is why its identification is crucial in molecular biology and oncology. The location of the HER2 gene on this specific chromosome has implications for genetic testing and treatment strategies in cancers that exhibit HER2 overexpression. Understanding this gene's placement allows for better screening techniques and the development of targeted therapies, such as trastuzumab (Herceptin).