What is the name of the major histocompatibility complex genes found in humans?

The major histocompatibility complex (MHC) genes in humans are known as Human Leukocyte Antigen (HLA) genes. These genes play a crucial role in the immune system by encoding proteins that present peptide fragments to T cells, which are vital for recognizing foreign substances and triggering an immune response. The HLA system is fundamental for the body’s ability to differentiate between self and non-self, which is critical for transplant compatibility and autoimmune disease susceptibility.

The HLA genes are highly polymorphic, meaning there is a vast variety of alleles within the population, contributing to individual differences in immune responses. This complexity is essential for the adaptability of the immune system in responding to a wide range of pathogens.

Understanding the role of HLA in organ transplantation, disease susceptibility, and immune responses is vital for healthcare professionals working in molecular biology and related fields. Thus, the designation of HLA distinctly identifies these gene products and their significance in human immunology.