Which chromosome deletion is characteristic of Williams syndrome?

Williams syndrome is a genetic condition caused by a specific deletion of genetic material on chromosome 7, particularly within the region of 7q11.23. This deletion involves the elastin gene and results in a range of developmental and physical characteristics associated with the syndrome, including cardiovascular problems, distinctive facial features, and cognitive challenges. The deletion affects the structure and function of various tissues and organs, leading to the symptoms seen in individuals with Williams syndrome.

The characteristics of the syndrome are directly linked to the genetic alterations on this specific chromosome segment, making the association clear. The identification of this deletion is crucial for diagnosis and understanding the implications for individuals affected by the condition.

In contrast, the other options refer to different chromosome regions involved in other syndromes or conditions, such as deletions on chromosome 5p associated with Cri du Chat syndrome, deletions on chromosome 21q linked to other genetic disorders, or Trisomy 13 related to Patau syndrome. Understanding these differences helps clarify the genetics behind Williams syndrome and highlights the specificity of chromosomal deletions in various genetic disorders.