Which of the following DNA polymerases is not found in eukaryotes?

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Prepare for the ASCP Molecular Biology (MB) Technologist Exam. Study with flashcards and multiple-choice questions, each with hints and explanations. Get ready to succeed!

The correct answer is that DNA polymerase III is not found in eukaryotes. DNA polymerase III is primarily known as the main enzyme responsible for DNA replication in prokaryotes, specifically in bacteria such as Escherichia coli. It plays a critical role in synthesizing new DNA strands by adding nucleotides complementary to the template strand during cell division.

In contrast, eukaryotes possess several unique DNA polymerases. For instance, DNA polymerase α is involved in the initiation of DNA replication, while polymerases β and δ participate in DNA repair and replication processes. DNA polymerase δ, particularly, acts as the primary enzyme for synthesizing the lagging strand during DNA replication. Each of these polymerases has evolved to fulfill specific functions that are essential for the complex processes occurring within eukaryotic cells.

Thus, the absence of DNA polymerase III in eukaryotic organisms is significant, as it underscores the differences in DNA replication mechanisms between prokaryotic and eukaryotic cells.

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