Whole genome amplification (WGA) is primarily used for which of the following purposes?

Whole genome amplification (WGA) is primarily utilized for the purpose of generating a significant amount of DNA from a small initial sample. This method is particularly valuable in scenarios where the available genetic material is limited, such as in single-cell analyses or samples with low DNA yields. By amplifying the entire genome, WGA enables comprehensive genetic analyses, including microorganism typing and assessing the presence of genetic lesions.

When applied to microorganism typing, for example, WGA allows for the identification and characterization of different strains by producing enough DNA to carry out detailed genetic analyses, such as sequencing. Similarly, for screening for genetic lesions, whole genome amplification permits a thorough examination of potential mutations, variations, or abnormalities across the entire genome, facilitating an in-depth understanding of genetic conditions or diseases.

This capability is in contrast to methods focused on just amplifying single genes, which would not provide the vast genetic landscape that WGA captures. Additionally, WGA does not involve the detection of specific protein markers, as that pertains to different types of assays and techniques, nor is it primarily used for graphical representation, which represents the visualization of data rather than the amplification of genomic material itself. Thus, the primary utility of WGA in context is for comprehensive genetic analysis, particularly